| 210 | 3 | 23 |
| 下载次数 | 被引频次 | 阅读次数 |
以2,6-二氯苯胺为原料,经重氮化,取代反应、缩合、水解、脱羧反应制得3-氯-2-硝基甲苯。本文系统地研究了其中的水解和脱羧反应,对主要的工艺参数进行了优化,确定了最佳反应条件。
Abstract：The paper relates to the synthesis of 3-chloro-2-nitrobenzene. Using 2,6-dichloroamine benzene as reaction material through diazo, substitution, hydrolization and condensation can be synthesized 3-chloro-2-nitrobenzene. The best condition of synthesis is foun. The invention mainly studies hydrolization and condensation process.
[1]NAKANOS,UMIOK,KARIYONEK,etal.Totalsynthesisofpyrrolnitrin,anewantibiotic[J].TetrahedronLetters,1996,7:737-740.
[2]GARCIAEE,BENJAMINLE,IANFRYERR.Enasmineinterediatesinthesynthesisofpyrrolnitritrin[J].HeterocyclChem,1974,11(2):275-277.
[3]HERBERTSINGER,WILLIAMSHIVE.Synthesisof7-indolecarboxylicacid[J].JAmChemSoc,1995,77:5700-5702.
[4]ARSHADAHMAD,LINDAJ.Nucleophilicsubstitutionofhalogensinhalogenoquinoxalino[2,3-c]cinnolincs[J].JChemSocPerkinTrans,1994,1:2751-2758.
[5]藤龙雄.2-ニトロトルユン诱导体の制造法[P].JP:63158926,1990-01-12.
[6]SHIMADA.Processforthenitrationofhalogenatedbenzenederivaties[P].US:3966830,1976-06-29.
[7]VICENTJ.Ylidemethylationofaromatcnitrocompounds[J].JOrgChem,1996,1:243-247.
[8]顾可权.重要有机化学反应[M].上海:上海科学技术出版社,1982.
基本信息:
中图分类号:TQ246.13
引用信息:
[1]陈磊,冯荣秀,张静,孙国鹏,宋健.3-氯-2-硝基甲苯的合成研究[J].化学工业与工程,2003(02):76-79.